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临床试验/NCT02573441
NCT02573441已完成不适用

KEYS to Succeed: Cognitive and Academic Intervention Program for Children and Adolescents Surviving Cancer

The Hospital for Sick Children2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2015年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
28
试验地点
2
主要终点
Wechsler Intelligence Scale for Children - Fourth Edition Integrated

研究概览

简要总结

The study will examine whether school liaison services and home-based parental tutoring can help with academic difficulties of paediatric brain tumour survivors who received cranial spinal radiation and have returned to school. Forty-five patients will participate in the project. All patients will receive psychology liaison services to link resources at the hospital with those in the community. Patients will participate in one of two tutoring programs designed to directly or indirectly improve math skills over 12 weeks. Weekly phone calls will be used to support parents using the program. Patients will be tested before, immediately after, and six months following each tutoring program to assess growth in mathematics and working memory abilities.

详细描述

Paediatric brain tumour survivors who receive cranial spinal radiation have learning problems, particularly in mathematics and working memory. Working memory is often described as a "mental workspace" where relevant information is held in mind and processed. Working memory is important in mathematics for holding in mind relevant information and carrying out steps necessary to solve problems.

This study will examine whether school liaison support and home-based parental tutoring can help address the academic difficulties of paediatric brain tumour survivors who have received cranial spinal radiation and who have returned to their community school. Forty five patients will participate in the project. First, all patients will receive psychology liaison services to link resources at the hospital with those in the community in order to provide information regarding the effects of pediatric cancer on learning and facilitate the implementation of appropriate assistive technology and remediation programs. Patients will then participant in one of two tutoring programs over the course of a 12 week period. One group of patients will participate in a program that addresses working memory with the intent of indirectly helping with mathematics skills. This program will be delivered over the internet. Another group of patients will participate in a program using a work book to directly help improve mathematics skills. Weekly phone calls will be used to support parents in doing the program. Patients will be tested before, immediately after, and six months following each tutoring program to assess growth in mathematics and working memory abilities. The two intervention programs will be compared to a waitlist control group that receives only the liaison service (including academic support through weekly phone calls over the 12 weeks).

The findings from this study will provide evidence about the type of intervention that is most effective at helping paediatric brain tumour survivors improve their mathematics skills and working memory ability.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
6 Years 至 17 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Has been diagnosed with a brain tumour and treated with cranial radiation
  • Is between 1 and 10 years following diagnosis
  • Has English as his or her native language or has had at least two years of schooling in English
  • Is between the ages of 6 and 17
  • Less than a Grade 8 equivalent math score

排除标准

  • Is younger than 6 years or older than 17 years of age
  • Is receiving palliative care

结局指标

主要结局

Wechsler Intelligence Scale for Children - Fourth Edition Integrated

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of verbal and visual working memory

Woodcock Johnson Academic-Third Edition

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of math Fluency, applied math problems, and qualitative concepts

Behaviour Rating Inventory of Executive Function-Parent Version

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of executive functioning

Wide Range Assessment of Memory and Learning - Second Edition

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of verbal and visual working memory

Automated Working Memory Assessment

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of verbal and visual working memory

Connors' Continuous Performance Test-Second Edition

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of sustained attention

Monitoring Basic Skills Progress

时间窗: Pre-intervention, 12 weeks after intervention and 6 months follow-up

A measure of mathematics

次要结局

  • SAM(Pre-intervention, 12 weeks after intervention and 6 months follow-up)
  • California Verbal Learning Test, Children's Version(Pre-intervention, 12 weeks after intervention and 6 months follow-up)
  • Delis-Kaplan Executive Function System(Pre-intervention, 12 weeks after intervention and 6 months follow-up)
  • CANTAB(Pre-intervention, 12 weeks after intervention and 6 months follow-up)
  • Wechsler Abbreviated Scale of Intelligence - Second Edition(Pre-intervention, 12 weeks after intervention and 6 months follow-up)
  • Wide Range Assessment of Memory and Learning - Second Edition(Pre-intervention, 12 weeks after intervention and 6 months follow-up)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Donald Mabbott

Program Head, Neurosciences & Mental Health

The Hospital for Sick Children

研究点 (2)

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