Evaluation of atorvastatine -as an adjuant- in reduction of negative symptoms in schizophrenic inpatients

Jundishapur University of Medical Sciences0 个研究点目标入组 40 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•a diagnosis of schizophrenia according to DSM-IV-TR; an overall score of 50 or higher on the PANSS scale; 15 or higher negative score in PANSS scale; age range between 70-18 years; duration of at least 1 year from onset of the illness. Exclusion criteria: history of sensitivity to statins; active liver disease or inexcusable stable increase in liver enzymes ; renal failure; serious medical illness; substance abuse or dependency in recent months; pregnancy; lactation; other simultaneous psychiatric disorders requiring medication; desire to homicide or suicide; having dementia and severe cognitive impairments not bound to schizophrenia; organic brain disorders such as seizure; severe mental retardation and Parkinsonism; consumption of oral antipsychotics during last month or long-acting Injectable forms within three months; Concomitant use of other drugs such as antidepressants; lithium which may interfere in treatment; drug-resistant schizophrenia disorder;, lack of response to appropriate dosage and duration of Risperidone.

发起方

Jundishapur University of Medical Sciences