A Clinical Study to see the effectiveness of Guda-Haritaki (Jaggery with Terminalia Chebula fruit) in Kaphaja Pratishaya (Allergic Rhinitis) in children ?
- Conditions
- Health Condition 1: J310- Chronic rhinitis
- Registration Number
- CTRI/2019/04/018778
- Lead Sponsor
- Dattatray Chavan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 197
Children are with symptoms of Kaphaja Pratishaya (Allergic Rhinitis) of age 6 to 12 years1.
Patients will be selected irrespective of sex and religion.
Patients, whose parents are willing to participate their child in the study and
are ready to sign informed consent form will be selected for the study.
Children with symptoms of Allergic Rhinitis occur for > 4 days per week and / or for > 4 consecutive weeks at a time.
The laboratory finding of increased numbers of eosinophils in the nasal mucosal smear (presence of > 4 % eosinophils for 6 to 10 years of age and >10 % eosinophils for 11 to 12 years of age) and elevated Total Serum IgE concentration ( > 20 IU/ml)that patients will be selected.
Patients with nasal abnormalities like D.N.S., Nasal polyps, adenoid and tonsilar hypertrophy.
Patients with acute respiratory infection or severe concomitant disease (Tuberculosis, Pneumonia).
Malnourished child.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect on change in symptoms (Nasal congestion, Nasal obstruction, Nasal itching, Clear Rhinorrhea, Sneezing and conjuntival irritation) of Allergic Rhinitis at 28th day. <br/ ><br> <br/ ><br>To evaluate the effect on change in eosinophils in nasal smear, serum IgE concentration and Absolute eosinophil count (AEC) at 28th day.Timepoint: 28th day.
- Secondary Outcome Measures
Name Time Method To evaluate the effect on change in symptoms (Nasal congestion, Nasal obstruction, Nasal itching, Clear Rhinorrhea, Sneezing and conjuntival irritation) of Allergic Rhinitis at 14th day. <br/ ><br> <br/ ><br>Quality of life in children with Allergic Rhinitis at the first follows up visit i.e. at 14th day, 28th day and on 45th day.Timepoint: 14th day, 28th day and on 45th day.