Comparison of Outcomes With Stapler Versus Hand-Sewn Closure of the Pancreatic Stump Following Minimally Invasive Distal Pancreatectomy: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 384
- 试验地点
- 1
- 主要终点
- Postoperative pancreatic fistula (POPF)
研究概览
简要总结
The incidence of postoperative pancreatic fistula (POPF) after Distal pancreatectomy (DP) remains high. Of the available mitigation strategies, high-quality closure of the pancreatic stump is fundamental.
Researchers failed to find a decrease in the incidence of POPF after stapler closure of the pancreatic stump compared with that related to hand-sewn suture in DP. Minimally invasive DP (MDP) is becoming the first choice for patients and surgeons, few studies have evaluated whether stapler closure is superior to hand-sewn suture for stump closure in MDP.
Therefore, this retrospective study was aimed at evaluating the effect of stapler versus hand-sewn closure on the incidence of POPF after MDP.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Underwent elective minimally invasive pancreatic body and tail resection with or without splenectomy
排除标准
- •Incomplete medical records
- •History of previous pancreatic operations
- •Emergent operation
- •Conversion to open pancreatectomy
- •Receipt of wedge resection or other procedures
结局指标
主要结局
Postoperative pancreatic fistula (POPF)
时间窗: Within 3 months after pancreatic surgery
The outcome was POPF per the International Study Group of Pancreatic Surgery definition
次要结局
- postpancreatectomy hemorrhage (PPH)(Within 3 months after pancreatic surgery)
- Surgical complications(Within 3 months after pancreatic surgery)
- delayed gastric emptying (DGE)(Within 3 months after pancreatic surgery)
- Chyle leak(Within 3 months after pancreatic surgery)
研究者
TingBo Liang
Professor
Zhejiang University