Enhanced Assessment of Fluid resuscitation in ICU :role of VEXUS, E- VEXUS and Lung Ultrasound
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- to evaluate whether incorporating extended VEXUS score into the existing VEXUS protocol with lung ultrasound score (LUS) enhances the sensitivity and timely identification of fluid overload in ICU patients.
研究概览
简要总结
Patient with hypotension with MAP less than 60 mm Hg, will be screened further, the patients with IVC collapsibility index of more than 50 % or distensibility index of more than 18% with IVC diameter of less than 2 cm and who meet all the inclusion criteria will be resuscitated with fluid bolus of 20 ml /kg over an hour , if the patient doesn’t respond then another fluid bolus of 10 ml/kg will be given . If the patients starts responding to fluids , then the maintenance fluids will be given . Following this, POCUS will be performed at 1st hour , 3rd hour, 6th hour , 12th hour , 24 hour till 48 hours to look for IVC distensibility or collapsibility index with diameter and lung ultrasound for B-Lines evaluation .If the IVC diameter is more than 2 cm with distensibility index of less than 18% or collapsibility index of less than 50% , then we will perform VEXUS with femoral vein for Extended VEXUS to look for venous congestion and associated organ dysfunction .Then the final score of mild, moderate and severe will be calculated by adding B- line lung ultrasound score, with VEXUS and extended VEXUS score.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •All Patients admitting in ICU and Patients who aged 18 years or older with sepsis, poisoning , meningitis, encephalitis in shock.
排除标准
- •patient relatives who will not give consent 2.Patients with Liver failure.
- •Patients with pneumonia, ARDS, pleural effusion.
- •Patients with cardiogenic shock.
结局指标
主要结局
to evaluate whether incorporating extended VEXUS score into the existing VEXUS protocol with lung ultrasound score (LUS) enhances the sensitivity and timely identification of fluid overload in ICU patients.
时间窗: BASELINE, 1 HOUR , 3 HOUR , 6 HOUR , 12 HOUR , 24 HOUR , 48 HOUR
次要结局
-  To evaluate the possible relation between the extended VEXUS with VEXUS grade with B line Ultrasound and the adverse effects of intensive fluid administration(POCUS will be performed at 1 hour, 3 hour , 6 hour ,12 hour, 24 hours till 48 hours)
研究者
Dr Swati Taneja
Institute of Medical Sciences, Banaras Hindu University