CTRI/2024/08/071934Not yet recruitingPhase 3
Comparison of Nitro-glycerine spray and Lignocaine spray for attenuating the pressor response during laryngoscopy and endotracheal intubation in patients undergoing elective surgery under general anaesthesia
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Peoples Hospital
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Attenuation of pressor response
Study Overview
Brief Summary
This is a postgraduate thesis to study the attenuation response of nitroglycerine spray and 10% lignocaine spray. This study comprises of 120 patients divided into 2 groups. One group will recieve Nitroglycerine spray and the other will receive lignocaine spray prior to laryngoscopy. The stress response during laryngoscopy will be recorded for 10 minutes and compared.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Asa grade 1 and 2 Elective surgery under general anaesthesia with endotracheal intubation.
Exclusion Criteria
- •Lack of patients consent Age less than 18 years and more than 60 years ASA grade 3 and more Patient with anticipated difficult airway Patient with hypersensitivity to any of the drugs used Pregnant and lactating mothers Hypertensive patients.
Outcomes
Primary Outcomes
Attenuation of pressor response
Time Frame: 10 minutes
Secondary Outcomes
- Hemodynamic parameters(10 minutes)
Investigators
Dr Pushpraj Brahme
Peoples College of Medical Sciences and Research Centre
Study Sites (1)
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