An Intervention Trial to Prevent Cognitive Impairment and Depression in Older Me

Completed

• Conditions: Cognitive impairment; Depression; Neurological - Other mental health disorders; Mental Health - Depression

• Registration Number: ACTRN12605000045617
• Lead Sponsor: HMRC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-07-26
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 300

Inclusion Criteria

Men over the age of 75 years with a previous history of hypertension

Exclusion Criteria

Significant cognitive impairment or depression at baseline, the presence of severe illness likely to cause the subject's death within 12 months, residence in a nursing home or long stay hospital,currently taking B group vitamins or food supplements and those subjects who are unable to complete the studys instruments in English.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
[]

Secondary Outcome Measures

Name	Time	Method
Other cognitive measures including MMSE, Clock Drawing Test, California Verbal Learning Test and Test of Attention.[];Depression measures include Beck Depression Inventory and Geriatric Depression Scale.[];Also changes in Quality of Life as determined by SF 36.[];Laboratory measures include changes in vitamin, homocysteine and A beta protein levels.[]