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Safety and Efficacy of a Hypoglossal Nerve Implant for the Treatment of Obstructive Sleep Apnea (OSA)

Not Applicable
Completed
Conditions
Sleep Apnea, Obstructive
Signs and Symptoms, Respiratory
Sleep Apnea Syndromes
Respiration Disorders
Syndrome, Obstructive Sleep Apnea
Interventions
Device: aura6000 System
Registration Number
NCT01532180
Lead Sponsor
ImThera Medical, Inc.
Brief Summary

The objective of the study is to determine the safety and preliminary efficacy in patients utilizing the aura6000 System for the treatment of Obstructive Sleep Apnea (OSA).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
14
Inclusion Criteria
  • Moderate to severe obstructive sleep apnea (AHI 15 to 60).
  • Cannot or will not tolerate CPAP treatment.
  • Body mass index (BMI) between 25 and 40
  • Able to read, understand, sign and date the written informed consent form
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
THN Therapyaura6000 System-
Primary Outcome Measures
NameTimeMethod
Adverse events and Serious Adverse events peri and post-operatively3 and 12 months post-operative
Mean change in AHI measured through in-lab polysomnography (PSG) compared to baseline.3 and 12 months post-implant
Secondary Outcome Measures
NameTimeMethod
Mean change in Quality of Life outcomes measured with FSS (Fatigue Severity Scale) as compared to baseline.3 and 12 months post-implantation
Mean change in Quality of Life outcomes measured with ESS (Epworth Sleepiness Scale) as compared to baseline.3 and 12 months post-operative

Trial Locations

Locations (1)

Clinique Univ. Saint-Luc

🇧🇪

Brussels, Belgium

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