JPRN-UMIN000006164已完成未知
Study of UGT1A1*27 gene polymorphism for irinotecan therapy - Study of UGT1A1*27 for irinotecan
ung Oncology Group in Kyusyu0 个研究点目标入组 50 人开始时间: 2011年8月12日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
Fifty patients were enrolled, with 48 patients determined eligible. UGT1A1 polymorphisms 28/28, 6/6, 28/-, 6/-, -/-, observed 0 (0%), 1(2%), 1(2%), 7(15%), 17(35%), and 22(46%), respectively. UGT1A1*27 were examined in 9 patients including one ineligible patient, however, no polymorphisms were found.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) interstitial pneumonia in chest X-ray 2) with active infection 3) with active the other malignancies 4) pregnancy or possible pregnancy 5) mental diesease difficult to attend the study 6) high fever >= 38 degree 7) severe complication: myocardial infarction within 3 months, uncontrolled angina pectoris, heart failure, diabetes mellitus, hypertension 8) diarrhea 9) paralysis of intestine or ileus
研究者
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