The Effect of Concentrated Pomegranate Juice Consumption on Lipid Profile and Inflammatory Factors in Patients With Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 试验地点
- 1
- 主要终点
- HDL- Cholesterol change
研究概览
简要总结
The aim of this study is to examine the effects of concentrated pomegranate juice on serum lipid profile and some inflammatory factors in patients with type 2 diabetes. Forty patients aged between 25-60 years old from both sexes are recruited. Patients consume 50gr/day concentrated pomegranate juice for 4 weeks. Anthropometric and blood pressure measurements, 3-days food-record questionnaire ,physical activity and fasting blood samples were collected at the beginning and at the end of the study. Fasting blood sugar, lipid profile, TNF- a, IL-6,hs -CRP and adiponectin levels are measured. LDL are calculated by formula. The participants are asked not to change their regular diet, medicine and activity during the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •male or female 25 to 60 years old
- •having type 2 diabetes for at least 6 month
排除标准
- •pregnancy
- •lactation
- •cardiac disease
- •hepatic disease
- •respiratory disease
- •chronic renal diseases
- •acute or chronic inflammation
- •retinopathy
- •intake of antioxidant supplement
- •insulin therapy
- •sensitivity to concentrated pomegranate juice
- •change oral drug for controlling blood glucose
结局指标
主要结局
HDL- Cholesterol change
时间窗: Baseline and after 4 weeks
adiponectin change
时间窗: Baseline and after 4 weeks
Triglyceride change
时间窗: Baseline and after 4 weeks
Total Cholesterol change
时间窗: Baseline and after 4 weeks
hsCRP change
时间窗: Baseline and after 4 weeks
TNF- α change
时间窗: Baseline and after 4 weeks
IL-6 change
时间窗: Baseline and after 4 weeks
LDL- Cholesterol change
时间窗: Baseline and after 4 weeks
次要结局
- Fasting Blood Sugar change(baseline and after 4 weeks)
- Body Mass Index change(baseline and after 4 weeks)
- Blood Pressure change(Baseline and after 4 weeks)
研究者
Maryam Zare
Nutritionist
Ahvaz Jundishapur University of Medical Sciences