Effect of Functional Treatment on Mandibular Asymmetric Growth

Completed

• Conditions: Temporomandibular Joint Disorder
• Interventions: Device: Distraction splint therapy

• Registration Number: NCT01113177
• Lead Sponsor: University of Aarhus

Brief Summary

Temporomandibular joint (TMJ) arthritis is known to alter the mandibular development in children diagnosed with juvenile idiopathic arthritis. In a number of cases a genuine breakdown of cartilage and bone is seen in the affected joint which leads to asymmetric mandibular growth in the affected side. In cases of unilateral TMJ involvements severe mandibular asymmetric mandibular growth deviations are seen. We hypothesize that these growth deviations can be minimized and controlled by the use functional orthodontic appliance therapy.

Detailed Description

This is a retrospective study design with the aim to evaluate the clinical procedures we have used the last 15 years to treat JIA patients with unilateral TMJ arthritis. More specifically, the purpose is to evaluate the mandibular growth in all JIA patients with unilateral TMJ arthritis and an asymmetric mandibular growth pattern treated with non-surgical distraction splint therapy between 1994 and 2010 at the dep. of Orthodontics, Aarhus University, Denmark. The evaluation is based on radiological examinations at the beginning of their non-surgical distraction treatment as well as after the patients have finished their distraction-splint therapy.

Study Timeline

• Study Start: 1994-06
• Study First Submitted: 2010-03-15
• Study First Submitted QC: 2010-04-27
• Study First Posted: 2010-04-29
• Primary Completion: 2010-09
• Study Completion: 2010-10
• Status Verified: 2010-11
• Last Update Submitted: 2010-11-08
• Last Update Posted: 2010-11-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• Juvenile Idiopathic arthritis patients diagnosed with unilateral temporomandibular joint arthritis and an asymmetric mandibular growth pattern

Exclusion Criteria

• Juvenile Idiopathic arthritis patients diagnosed with bilateral temporomandibular joint arthritis
• Juvenile Idiopathic arthritis patients with no mandibular growth potential left.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Distraction splint therapy	Distraction splint therapy	All JIA patients with asymmetric mandibular growth due to unilateral TMJ arthritis are offered non-surgical functional orthodontic splint therapy with a distraction splint. Mandibular growth is thereafter evaluated in the affected side compared with the mandibular growth in the healthy side of the same individual.

Primary Outcome Measures

Name	Time	Method
Mandibular growth in children with unilateral TMJ arthritis treated with an acrylic distraction splint	average treatment with splint is 6.4 years	The craniofacial dimensions are measured radiologically prior to the start of the treatment with the distraction splint. Second measurements of the craniofacial dimensions are evaluated after the patients have ended the treatment with the distraction splint. In that way we are able to evaluate the craniofacial growth in the affected side compared to the craniofacial growth in the "healthy" side in JIA patients with unilateral TMJ arthritis. The succces of the distraction splint treatment is decided based the splints ability to normalize the craniofacial growth in the affacted side.

Trial Locations

Locations (1)

Dep. of Orthodontics, Aarhus University; 🇩🇰 Aarhus, Denmark