PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars

Not Applicable

Completed

• Conditions: Irreversible Pulpitis
• Interventions: Procedure: Mineral trioxide aggregate; Procedure: Biodentine; Procedure: portland cement

• Registration Number: NCT04784949
• Lead Sponsor: Fayoum University

Brief Summary

this study aimed to compare the clinical and radiographic outcomes of full pulpotmy after application of Biodentine, or MTA, or Portland cement above PRF membrane In permanent molars with irreversible pulpitis

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-01
• Primary Completion: 2020-08-01
• Study Completion: 2021-01-01
• Status Verified: 2021-03
• Study First Submitted: 2021-03-02
• Study First Submitted QC: 2021-03-03
• Last Update Submitted: 2021-03-03
• Study First Posted: 2021-03-05
• Last Update Posted: 2021-03-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• spontaneous, lingering pain exacerbated by hot and cold , and/or radiating pain
• Responded to cold and electric pulp testing

Exclusion Criteria

• pain on palpation, percussion,
• mobility or swelling
• peridontall widening
• Teeth with marginal periodontitis or crestal bone loss
• resorption
• calcified canals

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mineral trioxide aggregate	Mineral trioxide aggregate	pulpotomy with PRF and Mineral trioxide aggregate
Biodentine	Biodentine	pulpotomy with PRF and Biodentine
Portland cement	portland cement	pulpotomy with PRF and white Portland cement

Primary Outcome Measures

Name	Time	Method
Change in postoperative pain	24 hours, 48 hours, 1 week, every 3 months for 12 months	persistence , relief , or exacerbation of pain using visual analogue scale for pain score
Change in swelling	24 hours, 48 hours, 1 week, every 3 months for 12 months	appearance of periapical swelling or facial swelling after the clinical procedures (Binary outcome: Yes/No)
Change in Mobility	24 hours, 48 hours, 1 week, every 3 months for 12 months	appearance of teeth mobility after the clinical procedures (record of periodontal pocket depth)

Secondary Outcome Measures

Name	Time	Method
calcific like bridge	12 month	measure of the calcific bridge thickness using CBCT

Trial Locations

Locations (1)

Faculty of dentistry Fayoum University; 🇪🇬 Fayoum, Egypt