The Beyond Ageing Project: A selective prevention trial using novel pharmacotherapies in an older age cohort at risk for depressio

Phase 3

Active, not recruiting

• Conditions: depression; cognitive decline; Mental Health - Depression; Mental Health - Studies of normal psychology, cognitive function and behaviour; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12610000032055
• Lead Sponsor: niversity of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-01-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 205

Inclusion Criteria

To be eligible participants must:
- Have provided written informed consent before any trial procedures are undertaken
- Be aged 60 years or older, and
- have a lifetime history of depressive symptoms (defined as a K-10 score ranging from 16 to 29) meaning that participants included in the trial will be at greater risk of depression.

Exclusion Criteria

Participants will be excluded if they: - Have a history of stroke/other serious cerebro or cardiovascular illness, neurological, psychiatric or neurodegenerative disease or other significant illness; Show clinically relevant levels of depression on the Patient Health Questionnaire (PHQ-9) at the time of screening or, receive a diagnosis of depression based on the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID-I) at the time of completing the medical assessment; Are suicidal at the time of screening or at the time of completing the medical assessment; Show abnormal liver function or; Are currently taking anti-depressant medications and it is deemed unadvisable by the trial psychiatrist to cease these medications for the period of the trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified