ACTA-PORT Score as a Predictor of Acute Kidney Injury in Addition to Blood Transfusion in Cardiac Surgery: Extending Its Clinical Utility
- Conditions
- Cardiac DiseaseBlood TransfusionAcute Kidney Injury
- Registration Number
- NCT06484907
- Lead Sponsor
- Ankara City Hospital Bilkent
- Brief Summary
In the scope of this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.
- Detailed Description
ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) score is a simple, reliable, and validated tool used to predict the risk of transfusion in patients undergoing heart surgery. In calculating ACTA-PORT score, age, gender, hemoglobin, body surface area, EuroSCORE, creatinine, and type of operation are used.
In this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.
The files of patients undergoing open heart surgery in the cardiovascular surgical operating rooms of Ankara Bilkent City Hospital, along with anesthesia records, transfusion records, and test results identified through the Hospital Information Management System, will be prospectively evaluated. Data will be collected after patients are admitted to the intraoperative and postoperative intensive care unit.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 467
- Patients over 18 years old
- Patients having open heart surgery
- Patients undergoing surgery by using cardiopulmonary bypass pump
- Patients under 18 years old
- Patients diagnosed with kidney disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method KDIGO AKI Staging Preoperative (last week before operation) and daily after the operation for 7 days KDIGO is in the process of developing the Clinical Practice Guideline for Acute Kidney Injury (AKI) and Acute Kidney Disease (AKD). ///// Stage 1: Serum creatinine 1.5-1.9 times baseline or ≥0.3 mg/dl (≥26.5 mmol/l) increase or Urine output \<0.5 ml/kg/h for 6-12 hours ////// Stage 2: Serum creatinine 2.0-2.9 times baseline or \<0.5 ml/kg/h for ≥12 hours /////// Stage 3: Serum creatinine 3.0 times baseline or Increase in serum creatinine to ≥4.0 mg/dl (≥353.6 mmol/l) or Initiation of renal replacement therapy or in patients \<18 years, decrease in eGFR to \<35 ml/min per 1.73 m² or Urine output \<0.3 ml/kg/h for ≥24 hours or anuria for ≥12 hours
- Secondary Outcome Measures
Name Time Method Mechanical Ventilation Duration the duration after surgery up to a month The duration the patient remains intubated from surgery to extubation
Reoperation Necessity the duration after surgery up to a month The need for reoperation due to bleeding
Intensive Care Duration the duration after surgery up to a month The duration the patient remains in intensive care unit after surgery
Complications the duration after surgery up to a month Cardiac, Pulmonary, Neurological, Infectious, Thrombotic complications and Presence of MODS (Multiple Organ Dysfunction Syndrome) / SIRS (Systemic Inflammatory Response Syndrome)
Hospital Stay Duration the duration after surgery up to a month The duration the patient stays in the hospital after surgery until discharge
Mortality the duration after surgery up to a month If the patient dies within 1 month or not
Trial Locations
- Locations (1)
Ankara Bilkent City Hospital
🇹🇷Ankara, Turkey