A prospective, observational study investigating the level of agreement between transcutaneous and invasive carbon dioxide measurements in critically ill emergency department patients

Not Applicable

Completed

• Conditions: Critical illness; Emergency medicine - Resuscitation

• Registration Number: ACTRN12619001431112
• Lead Sponsor: South Western Sydney Local Health District

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-16
• Study Completion: 2021-06-30
• Last Update Posted: 16 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Emergency department patient
Patient requiring hospital admission
Adult > 18 years of age
Arterial catheter required for ongoing care

Exclusion Criteria

Children (<18 years)
Patients not requiring arterial line

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transcutaneous Carbon Dioxide reading at the specified timepoints measured by a skin detector clipped to the earlobe of the patient using the Sentec Digital Monitor System.[0mins, 30mins, 60mins and 90mins post enrolment.];Arterial Carbon Dioxide reading at the specified timepoints, obtained on a sample taken from an arterial catheter (as part of standard care) and measured using a Radiometer ABL800 blood gas analyser.[0mins, 30mins, 60mins and 90mins post enrolment.]

Secondary Outcome Measures

Name	Time	Method
Presence of haemodynamic instability based on clinical examination (defined as systolic blood pressure below 90mmHg, Mean Arterial Blood Pressure below 60mmHg, or requirement for vasopressor support).[Once diagnosis becomes apparent, recorded at the time of assessment and treatment between 0mins and 90mins post enrolment.];Diagnosis of exacerbation of chronic obstructive pulmonary disease, based on bedside clinical assessment.[Once diagnosis becomes apparent, recorded at the time of assessment and treatment between 0mins and 90mins post enrolment.]