A RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED MULITCENTRIC TRIAL ON THE EFFECTS OF HOMOEOPATHIC MEDICINES ON CHRONIC RHINOSINUSITIS

Central Council for Research in Homoeopathy0 个研究点目标入组 120 人开始时间: 待定最近更新: 2021年11月24日

研究概览

暂无简介。

•1.Age group between 18-60 years from both gender.
•2.Patients suffering from chronic rhinosinusitis (with or without nasal polyps) as defined in European Position paper on rhinosinusitis and polyps 2007.i.e.
•-Presence of two or more symptoms one of which should be nasal blockage/ obstruction/congestion or nasal discharge (anterior/posterior nasal drip):
•- facial pain/pressure
•- reduction or loss of smell
•for >12 weeks with validation by interview.
•3 Written informed consent
•4 Patients who can act in accordance with the protocol

•1Patients who are not adequately symptomatic.
•2Patients with serious underlying medical condition (eg. Severe renal or hepatic disease)
•3Patients with history of malignancy.
•4Patients taken any medication prior to entry into the study (can be enrolled after wash out period of 15 days).
•5Patients taken topical steroids within 4 weeks before the study therapy (can be enrolled after wash out period of 1 month)
•6 Atrophic rhinitis
•7Complications of chronic rhinosinusitis
•8Significant psychological problems
•9Pregnant women
•10 Lactating mother
•11Do not give informed consent.
•12H/o of underlying immunodeficiencies, cystic fibrosis, bronchiectasis, chronic obstructive pulmonary disease, diabetes mellitus, neoplasia or fungal sinusitis.
•13Systemic diseases preventing participation in the study and medical and/or surgical treatments influencing the study.
•14 No prior paranasal sinus, nose surgery.

发起方

Central Council for Research in Homoeopathy