To compare effectiveness of two drugs fentanyl citrate versus lignocaine for decreasing the pressor response during artificial tube insertion in respiratory tube under general anaesthesia.
Phase 4
- Conditions
- Health Condition 1: 8- Other Procedures
- Registration Number
- CTRI/2023/09/057417
- Lead Sponsor
- SMS Medical College Jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients belonging to ASA ( american society of anaesthesiologist ) physical status grade one and two.
2. Patients willing to give written and informed consent.
3.Patients of either sex
4.Age group 20 to 50 years
Exclusion Criteria
1.Patients with history of known allergy to study drugs.
2.History of consumption of antihypertensive drugs ,sedatives , hypnotics ,and antidepressants preoperatively.
3.Pre-existing cardiovascular disease , significant respiratory , renal and hepatic disease .
4.History of drug and alcohol abuse.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the difference in changes in heart rate from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.
- Secondary Outcome Measures
Name Time Method To determine the difference in changes in hemodynamic responses (SBP,DBP,MAP ) from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.