A study to compare palonosetron with ondansetron for prevention of postoperative nausea vomiting (PONV) following gynaecological surgeries.
Phase 4
Completed
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: null- Prevention of postoperative nausea and vomiting (PONV) following laparoscopic gynaecological surgeries
- Registration Number
- CTRI/2018/03/012655
- Lead Sponsor
- Rohit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 130
Inclusion Criteria
ASA physical grade â?? I and II,
Non â??smoker
Weight â?? 40-90 kg
Surgery â?? Elective laparoscopic gynaecological surgeries.
Exclusion Criteria
Body weight > 90 kg
Known hypersensitivity to serotonin antagonists
History of motion sickness, PONV
Pregnant patients, Lactating mothers.
Patients with ongoing gastrointestinal disease
Disorder of any major organ function like liver, lung, heart or bone marrow.
Patients who received chemotherapy in last few weeks, who are on antiemetics, psychomimetics or steroids preoperatively.
Patients who are unable to cooperate with the investigators Patients who are not willing to participate in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method