CTRI/2019/04/018447进行中（未招募）未知
Investigation of influence of 5HT3B gene, ABCB1 gene and cytochromeP450 2D6 gene polymorphism in efficacy of antiemetic treatment with Ondansetron in post-operative south Indian female patients. A prospective observational study.
Rajiv Gandhi University of Health Sciences Bangalore0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •1.South Indian female population of age group between 20-60 years of age
- •All cases of Breast surgeries, Laproscopic hysterectomy and cholecystectomy surgeries and Mastoidectomy, administered with only Ondansetron intra operatively
排除标准
- •1.Very seriously ill patients who do not have somebody to accompany them because of the difficulty of interviewing such cases (getting the consent, lack tolerance of the pain or illness).
- •2.Patient refusal.
- •3. Patients who are on Cytochrome P450 inducers (eg, Rifampcin, Phenobarbitone, Phenytoin etc) or inhibitors ( eg, Quinidine, Fluoxetine, Haloperidol etc)
- •4. Cognitive dysfunction or any other inability to finish the interview.
- •5. Patients with concomitant diseases that might cause nausea or vomiting (eg, severe heart failure, ulcerations or obstructions of the upper gastrointestinal system, severe hepatic or renal dysfunction, and brain metastases).
- •6. Patients with prolonged QT interval
- •7. Patients with motion sickness
- •8. Pregnant patients.
研究者
相似试验
进行中（未招募）
1 期
The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of twice daily Tacrolimus and Advagraf - Pharmacogenetics of twice daily Tacrolimus and AdvagrafRenal transplantation.MedDRA version: 14.1 Level: LLT Classification code 10023438 Term: Kidney transplant System Organ Class: 100000004865EUCTR2009-013461-25-GBSt. George's, University of London330
招募中
不适用
Analysis of the effect of OATP1B3 genomic abnormality on hepatic ICG clearancechronic hepatitis CJPRN-UMIN000032781Tokai University37
已完成
不适用
The effect of one mutation in the ATP8B1 gene on hearing.liver diseaseNL-OMON33871niversitair Medisch Centrum Utrecht10
已完成
不适用
A Study of Pharmacodynamic and Genetic Parameters of Abira-DES Study Participants (NCT02217566) - Participants With Metastatic Castration-Resistant Prostate Cancer Treated With Abiraterone Acetate Following Unresponsive Treatment With DiethylstilbestrolMetastatic Castration-resistant Prostate CancerNCT04268628Janssen-Cilag Farmaceutica Ltda.42
招募中
不适用
tilization of 5HTT gene polymorphism as a prognostic indicator in cancercancer. We are recruiting patients with a known primary cancer of the following types: lymphoma, lung, gastrointestinal tumours, genitourinary tumours, hepatocellular cancer, breast, nasopharyngeal cancers). Adjustment for cancer type in the statisticall analysis will be done by including cancer type in the regression model.Cancer - Other cancer typesACTRN12610000028000niversity of Alexandria300