NL-OMON43515已完成不适用
Dapagliflozin on cholesterol metabolism in DM2: dissecting its effect on dyslipidemia by using stable isotope based cholesterol and glucose fluxes - DICE study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •-Male or postmenopauzal female patients with type 2 diabetes mellitus(HbA1C *6.5% - <8.5%)
- •-At least 12 weeks of stable dose metformin treatment, FPG<13.2 mmol/l
- •-LDL cholesterol >2.5 mmol/l
- •-Willing to switch used statin to rosuvastatin 10mg once daily for 9 weeks
- •-18-75 years of age
- •-Ability to provide informed consent
排除标准
- •-History of cardiovascular event
- •-exogenous insulin use
- •-Creatinin clearance < 60ml/min
- •-Alcohol abuse (>4 units/day)
- •-AST or ALT elevation (>2.5x upper limit)
- •-Contraindication to MR scanning (i.e. pacemaker, metallic foreign body, claustrophobia)
研究者
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