Memantine add on to treatment of refractory obssessive compulsive disorder: A double-blind clinical trial
Not Applicable
- Conditions
- Obsessive- Cumpulsive Disorder.Obsessive-compulsive disorder
- Registration Number
- IRCT138712141743N1
- Lead Sponsor
- Research Center for Behavioral Disorder and Substance Abuse, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Suffering from OCD, taking a therapeutic dose of a SSRI or Clomipramine, at least for 12 weeks, Y_BOSC score of 16 or greater Exclusion criteria: primary diagnosis of psychosis or bipolar mood disorder, substance abuse or dependency, uncontrolled medical condition, having had a pervious trial of Memantine, pregnancy or breast feeding, rising liver enzymes to more than twice of normal range during intervention, presence of MDD
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of symptoms of OCD. Timepoint: 4 weeks. Method of measurement: Y_BOCS and CGI Scale.
- Secondary Outcome Measures
Name Time Method