Multicenter study for diagnosing hepatic steatosis using attenuation measurement (ATT); Comparison with PDFF (MRI-determined proton density fat fraction).
Not Applicable
Completed
- Conditions
- Chronic liver disease
- Registration Number
- JPRN-UMIN000047411
- Lead Sponsor
- Ogaki Municipal Hospital
- Brief Summary
Bland-Altman analysis showed minimal fixed bias between iATT and MRI-PDFF with excellent reproducibility. The area under the curve to distinguish lipodystrophy grades 1, 2, and 3 was 0.887, 0.882, and 0.867, respectively. Skin to capsular distance greater than 25 mm was identified as the only significant factor causing discordance. no interaction between MRI-logPDFF and MRE-LSM on iATT values was observed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 846
Inclusion Criteria
Not provided
Exclusion Criteria
Patients without claustrophobia Patients without magnetic substance or tattoo Patients without pacemakers Patients judged as inappropriate for the study by the study responsibility (share) physician.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We assess the accuracy of ATT in assessing hepatic steatosis compared to PDFF
- Secondary Outcome Measures
Name Time Method We verify whether ATT can diagnose fatty liver (liver fat content 5% or more)