Effect of Sufentanil and Ropivacaine
Not Applicable
Completed
- Conditions
- Anesthesia Complications
- Interventions
- Registration Number
- NCT02488291
- Lead Sponsor
- Fudan University
- Brief Summary
The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.
- Detailed Description
A prospective study of 120 full-term parturients receiving labor analgesia were randomly assigned into 2 groups: the 0.5Sufen group (N=60), the 0.25Sufen group (N=60).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
- Patients had regular prenatal examinations at the outpatient clinic;
- They were between 25 to 35 years of age)
- They had a gestational age ≥37 weeks and < 42 weeks;
- They had an estimated fetal weight ≥ 2,500 g and < 4,200 g.
Exclusion Criteria
- a history of spinal surgery,
- platelet count <100×109 /L ,
- coagulation disorder,
- sensorimotor disorder of lower extremity,
- leg pain,
- puncture point infection,
- heart disease history,
- pulmonary disease,
- liver and renal function disorder and
- a history of neuropsychiatry drugs.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 0.5 sufentanil 0.1% ropivacaine 0.5µg/ml sufentanil, 0.1% ropivacaine for 6ml/h 0.5 sufentanil 0.5µg/ml sufentanil 0.5µg/ml sufentanil, 0.1% ropivacaine for 6ml/h 0.25 sufentanil 0.25 sufentanil 0.25µg/ml sufentanil, 0.1% ropivacaine for 6ml/h 0.25 sufentanil 0.1% ropivacaine 0.25µg/ml sufentanil, 0.1% ropivacaine for 6ml/h
- Primary Outcome Measures
Name Time Method VAS(visual analog pain score) 1 year comparison with two groups
- Secondary Outcome Measures
Name Time Method