Effect of 0.5µg/ml Sufentanil and Ropivacaine Towards Pregnant Women and Fetus in Analgesia Labor
Overview
- Phase
- Not Applicable
- Intervention
- 0.5µg/ml sufentanil
- Conditions
- Anesthesia Complications
- Sponsor
- Fudan University
- Enrollment
- 120
- Primary Endpoint
- VAS(visual analog pain score)
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.
Detailed Description
A prospective study of 120 full-term parturients receiving labor analgesia were randomly assigned into 2 groups: the 0.5Sufen group (N=60), the 0.25Sufen group (N=60).
Investigators
Zeyong Yang
Hospital
Fudan University
Eligibility Criteria
Inclusion Criteria
- •Patients had regular prenatal examinations at the outpatient clinic;
- •They were between 25 to 35 years of age)
- •They had a gestational age ≥37 weeks and \< 42 weeks;
- •They had an estimated fetal weight ≥ 2,500 g and \< 4,200 g.
Exclusion Criteria
- •a history of spinal surgery,
- •platelet count \<100×109 /L ,
- •coagulation disorder,
- •sensorimotor disorder of lower extremity,
- •leg pain,
- •puncture point infection,
- •heart disease history,
- •pulmonary disease,
- •liver and renal function disorder and
- •a history of neuropsychiatry drugs.
Arms & Interventions
0.5 sufentanil
0.5µg/ml sufentanil, 0.1% ropivacaine for 6ml/h
Intervention: 0.5µg/ml sufentanil
0.5 sufentanil
0.5µg/ml sufentanil, 0.1% ropivacaine for 6ml/h
Intervention: 0.1% ropivacaine
0.25 sufentanil
0.25µg/ml sufentanil, 0.1% ropivacaine for 6ml/h
Intervention: 0.25 sufentanil
0.25 sufentanil
0.25µg/ml sufentanil, 0.1% ropivacaine for 6ml/h
Intervention: 0.1% ropivacaine
Outcomes
Primary Outcomes
VAS(visual analog pain score)
Time Frame: 1 year
comparison with two groups