A Prospective Randomized Control Trial To Compare Post-Operative Pain And Complications After Colorectal Cancer Surgery Under Different Anaesthetic Techniques
Not Applicable
- Conditions
- Health Condition 1: C189- Malignant neoplasm of colon, unspecifiedHealth Condition 2: C19- Malignant neoplasm of rectosigmoidjunctionHealth Condition 3: C20- Malignant neoplasm of rectum
- Registration Number
- CTRI/2024/02/062355
- Lead Sponsor
- DR BRAIRCHAIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient undergoing surgery for colorectal carcinoma, of ASA grade 1,2,3
Exclusion Criteria
1.Patient refusal,
2.Allergy to propofol or any other drugs included in the study,
3.Chronic liver and kidney disease,
4.Inability to assess postoperative pain (post-operative mechanical ventilation),
5.Inability to understand and use intravenous patient controlled analgesia,
6.Early termination of intravenous patient controlled analgesia (re-do surgery, deterioration of patient status)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method post operative pain scoresTimepoint: at 1 ,2 ,4 ,8 12,16,20,24 hours in the postoperative period
- Secondary Outcome Measures
Name Time Method To compare the incidence of post-operative complications in the two different anaesthesia techniques until the day of discharge using Clavien – Dindo classificationTimepoint: till the day of discharge;To compare the opioid consumption in first 24 hours following surgery via intravenous patient controlled analgesia in both the groupsTimepoint: for first 24 hours;To find out the difference in between peri-operative inflammatory markers: change between preoperative (just before induction) and post- operative (24 hours after surgery) in IL-6, Neutrophil Lymphocyte ratio (NLR) Platelet Lymphocyte ratio (PLR) , Monocyte Lymphocyte ratio ( MLR).Timepoint: preopertaive sample and postoperative day 1