NCT00786526已完成不适用
Ventilator-Induced Diaphragmatic Dysfunction (VIDD) in Critically Ill Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 2
- 主要终点
- Respiratory function parameters
研究概览
简要总结
Animal studies showed that controlled mechanical ventilation (CMV) can induce dysfunction of the diaphragm, resulting in an early-onset and progressive decrease in diaphragmatic force-generating capacity, called ventilator-induced diaphragmatic dysfunction (VIDD).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Invasive mechanical ventilation (tracheally intubated or tracheotomized) less than 48h.·
- •Duration of mechanical ventilation for at least 72h.·
- •Subject itself or its next of kin has given written informed consent
排除标准
- •Patient is less than 18 years or more than 85 years of age·
- •The attending physician refuses to allow enrollment·
- •The patient refuses informed consent
- •Next of kin is unavailable or refuses informed consent·
- •Pregnant or breast-feeding female.
- •A pregnancy test will be performed in all female patients less than 60 years of age.·
- •Any contraindication to use cervical magnetic stimulation (mechanical cardiac assist device ...).·
- •Presence or suspicion of prior diaphragm injury or chronic disease·
- •Presence or suspicion of a central nervous system (CNS) disorder, including (but not limited to): CNS infarction, bleeding, tumor, or infection
结局指标
主要结局
Respiratory function parameters
时间窗: 6 weeks
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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