Evaluatıon of TREM-1, MMP-8 and TIMP-1 Levels in Perı-Implant Crevicular Fluıd of Perı-Implanted Indıvıduals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- TREM-1, MMP-8 and TIMP-1 levels in PICF samples
研究概览
简要总结
The aim of this study was to evaluate the relationship between Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1), Matrix Metalloproteinases-8 (MMP-8) and Tissue Inhibitors of Metalloproteinases-1 (TIMP-1) levels in peri-implant crevicular fluid (PICF) in peri-implantitis patients.
详细描述
The aim of this study was to evaluate the relationship between TREM-1, MMP-8 and TIMP-1 levels in peri-implant crevicular fluid (PICF) in patients with peri-implantitis, and the correlation of these markers with clinical periodontal parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Systemically healthy
- •Pregnancy or lactation
排除标准
- •osteoporosis
- •rheumatoid arthritis
- •autoimmune disease
研究组 & 干预措施
Peri-implantitis
Peri-implantitis is defined as bleeding on probing, suppuration, increased probing depth, clinical attachment loss, and radiographic bone loss
干预措施: Collection of PICF samples (Other)
Peri-implant Health
Peri-implant health is characterized by the absence of bleeding on probing, erythema, swelling, and suppuration in the peri-implant region
干预措施: Collection of PICF samples (Other)
结局指标
主要结局
TREM-1, MMP-8 and TIMP-1 levels in PICF samples
时间窗: 1 month
TREM-1, MMP-8, and TIMP-1 levels in PICF samples were measured by ELISA method
次要结局
未报告次要终点
研究者
Veli Özgen Öztürk
Principal Investigator
Aydin Adnan Menderes University