Renal sensing of the acidifying effect of sulphur-containing amino acids: consequences for the relation between protein intake and blood pressure
Completed
- Conditions
- ierfunctieverlies en hypertensieHypertensionraised blood pressure
- Registration Number
- NL-OMON32527
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 700
Inclusion Criteria
Male and female renal transplant recipients
Patients that are (beyond) one year after transplantation
Transplantation performed in de UMCG
Written informed consent
Exclusion Criteria
Dependence on renal dialysis
Severe general diseases or mental disorders making the participation in the study
impossible
Drug abuse
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Systolic and diastolic blood pressure</p><br>
- Secondary Outcome Measures
Name Time Method <p>Nierfunctie zoals weergegeven door creatinineklaring</p><br>
Related Research Topics
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What molecular mechanisms link sulfur-containing amino acids to blood pressure regulation in hypertension?
How does dietary protein intake affect renal acid excretion compared to standard-of-care antihypertensive therapies?
Which biomarkers correlate with protein-induced blood pressure changes in patients with chronic kidney disease?
What adverse events are associated with high sulfur amino acid consumption in hypertensive individuals with renal dysfunction?
Are there synergistic effects between amino acid metabolism modulators and ACE inhibitors in managing hypertension and kidney function?