NL-OMON38114
Completed
Phase 2
eo-adjuvant chemotherapy, cytoreductive surgery with hypethermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal origin. - NACHO-Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- peritoneal cancer
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 50
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Peritoneal carcinomatosis of colorectal origin diagnosed either by cytologic confirmation of malignant ascitis or by histologic or cytologic confirmation at laparotomy.
Exclusion Criteria
- •Age under 18 years
- •Previous chemotherapy, exept adjuvant cheomtherapy with an interval between adjuvant chemotheray and start of neo\-adjuvant chemotherapy of al least 12 months.
- •History of other malignancy, except basal cell carcinoma
- •Advanced liver disease, Child Pugh score \> 2
- •WHO performance status above 2
- •Unable to give written informed consent
- •Creatine clearance \< 30 ml/min
- •Liver or extra\-abdominal metastasis
- •Neurotoxicity \> grade 2 according to CTC AE 3\.0
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Not Applicable
Pre treatment with chemotherapy followed by surgery and removal of all intra-abdominal tumor and intra-peritoneal heated chemotherapy for peritoneal metastastasized colorectal cancer.EUCTR2010-020787-37-NLniversitair Medisch Centrum Groningen10
Recruiting
Not Applicable
Voorbehandeling met chemotherapie, verwarmde buikspoeling met chemotherapie na chirugische verwijdering van alle tumor bij patienten met buikvlies uizaaiingen van dikke darm of endeldarm kanker.peritoneal metastasis, colorectal cancer, surgery, cytoreduction,HIPECperitoneaal metastasen, chirurgie, neo-adjuvante chemotherapie, cytoreductie, HIPECNL-OMON22353niversity Medcal Center Groningen50
Completed
Phase 2
eo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertilitycervical cancercervical carcinoma10038594NL-OMON46384Antoni van Leeuwenhoek Ziekenhuis120
Active, not recruiting
Phase 1
eo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertilitywomen =18 and = 40 years with FIGO stage Ib1 cervical carcinoma with tumor measuring = 2 cm and = 4 cm on physical examination and imagingMedDRA version: 20.0Level: HLTClassification code 10008230Term: Cervix neoplasms malignantSystem Organ Class: 100000004864Therapeutic area: Diseases [C] - Cancer [C04]EUCTR2017-003102-40-NLKI-AV120
Active, not recruiting
Phase 1
Chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastasesThe CHARISMA randomized multicenter clinical trialEUCTR2013-004952-39-NLErasmus MC Cancer Institute224