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临床试验/CTRI/2025/11/096875
CTRI/2025/11/096875尚未招募不适用

Comparative Effectiveness of Individualised Homoeopathic medicine in Centesimal and 50 Millesimal Potency in the treatment of patients with Chronic Rhinosinusitis: An open label Prospective Randomised Controlled Trial.

National Institute of Homoeopathy1 个研究点 分布在 1 个国家目标入组 136 人开始时间: 2025年11月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
136
试验地点
1

研究概览

简要总结

CHRONIC RHINOSINUSITIS ICD CODE-11-MMS DIAGNOSIS CODE CAOA.Z

Chronic Rhinosinusitis (CRS) is a pervasive and debilitating inflammatory condition affecting the nose and paranasal sinuses. It is defined by symptomatic inflammation lasting a minimum of three months. The syndrome is clinically characterized by the persistent presence of at least two core symptoms for a minimum of 12 weeks, including nasal congestion or obstruction, anterior or posterior nasal discharge, an altered sense of smell (olfactory dysfunction), and facial pain or pressure. Patients who are suffering from Chronic Rhinosinusitis and registered in the OPD and IPD OF National Institute of Homoeopathy fulfilling the Inclusion and Exclusion criteria will be taken as sample of this Study. Dose and Frequency 0f the selected medicine as per the Homoeopathic Principle. Individualised medicine in centesimal and 50 Millesimal potency will be prescribed in accordance with randomised chart. Data of SNOT-22 , EQ-5D-5L and monarch scores will be assessed at baseline and after 4 months, to see the correlation, whether with the mean changes in SNOT-22 Score after using Individualised Homoeopathic Medicine in Centesimal and 50 Millesimal potency, will there also be a corresponding mean changes in EQ-5D-5L AND Monarch scores.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Participants in age group between 18-60 years.
  • Participants belonging to all gender, all religion and all socio-economic status.
  • Participants having Chronic Rhinosinusitis, for 12 weeks or more, fulfilling the diagnostic criteria of AAO-HNS Participants who can understand Bengali or Hindi or English; capable of filling the questionnaire.
  • Participants who are willing to participate in the study and giving informed written consent.

排除标准

  • Participants diagnosed with nasal polyps and the complications (mucous retention cyst, orbital cellulitis, meningitis, brain abscess etc.) of CRS.
  • Diagnosed cases of unstable psychiatric illness or some uncontrolled systemic diseases (like DM, Cancer and Thyroid diseases etc.), uncontrolled infections or any vital organ failure or immune-compromised patients.
  • Pregnant and lactating Women.
  • Substance abuse and or dependence or taking psychotropic drugs of modern medicine.
  • Participants who require surgical intervention for Chronic Rhinosinusitis.

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr BANDI KUSUMAPRIYA

National Institute of Homoeopathy

研究点 (1)

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