The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- distortion product auto acoustic emission
研究概览
简要总结
The aim of this study is to find the Effects of Anesthetics Used in Hypotensive Anesthesia on Stapes Reflex and Distortion Product Auto Acoustic Emission.
详细描述
This study was aimed at evaluating the effects of dexmedetomidine and esmolol on stapes reflex and distortion product auto acoustic emission. the stapes reflex and auto acoustic emission are of considerable diagnostic significances in otolaryngology this are objective methods for the assessment of auditory function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 age
- •American Society of Anaesthesiologists physical status classification (ASA)1-2
- •tympanoplasty surgery
- •patients with normal stapes reflexes
排除标准
- •hypertension
- •drug allergy
- •cardiac problems
- •pregnancy
研究组 & 干预措施
dexmedetomidine
0,4-0,8 µg./kg./h dexmedetomidine
干预措施: Dexmedetomidine (Drug)
esmolol
100- 300 µg./kg./min esmolol
干预措施: esmolol (Drug)
结局指标
主要结局
distortion product auto acoustic emission
时间窗: postoperative 1 day
distortion product measurements will be performed in 1001, 1501, 2002, 3003, 4004, 6006, 7996 Hz frequencies and change from baseline in distortion product measurements at postoperative 1 day
次要结局
- stapes reflex(postoperative 1 day)
研究者
Recep Aksu
associate professor
TC Erciyes University