跳至主要内容
临床试验/CTIS2023-508703-21-00
CTIS2023-508703-21-00招募中1 期

A Phase 1/2 Study to Evaluate the Safety and Efficacy of MK-2870 Monotherapy or in Combination With Other Anticancer Agents in Gastrointestinal Cancers - MK-9999-02A

Merck Sharp & Dohme LLC0 个研究点目标入组 139 人开始时间: 2024年3月20日最近更新:

试验速览

阶段
1 期
状态
招募中
入组人数
139

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 65+(—)
性别
All

入选标准

  • 1.Has one of the following cancers: •Unresectable or metastatic colorectal cancer •Advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) •Advanced and/or unresectable biliary tract cancer (BTC), 2.Has received one previous treatment for the cancer (colorectal cancer, PDAC); has received one or two previous treatments for BTC, 3.Has recovered from any side effects due to previous cancer treatment

排除标准

  • 1.History of severe eye disease, 2.Received prior treatment with a trophoblast cell surface antigen 2 (TROP2)-targeted antibody-drug conjugate (ADC)., 3.Received prior systemic anticancer therapy including investigational agents within 4 weeks before starting study intervention.

研究者

相似试验

进行中(未招募)
1 期
A trial to understand if AZD0486 is safe and helps in people with Relapsed or Refractory B-cell acute lymphoblastic leukemia (B-ALL)
CTIS2023-505840-20-00Astrazeneca AB153
招募中
1 期
AGN-193408 SR in the treatment of open-angle glaucoma or ocular hypertensioOcular hypertensionOpen-angle glaucoma
JPRN-jRCT2031220053Yamazaki Hayato84
进行中(未招募)
1 期
Study conducted to learn more about the safety and effects of CTX001 (the Study Therapy”) in patients with Severe Sickle Cell DiseaseMedDRA version: 20.0Level: PTClassification code 10043391Term: Thalassaemia betaSystem Organ Class: 10010331 - Congenital, familial and genetic disordersSickle Cell Disease
EUCTR2018-001320-19-ITVERTEX PHARMACEUTICALS INCORPORATED45
进行中(未招募)
1 期
A study to learn about the safety and efficacy of CTX001 (the study drug product) to treat Severe Sickle Cell DiseaseSevere Sickle Cell Disease (SCD)MedDRA version: 21.0Level: PTClassification code 10040641Term: Sickle cell anaemiaSystem Organ Class: 10010331 - Congenital, familial and genetic disorders
EUCTR2018-001320-19-GBVertex Pharmaceuticals Incorporated45
进行中(未招募)
1 期
An early study to test IMGN901 with carboplatin and etoposide for treating adult patients with certain types of cancer including small cell lung cancerPhase 2: small cell lung cancer (extensive-stage disease)MedDRA version: 14.1 Level: LLT Classification code 10049280 Term: Solid tumour System Organ Class: 100000004864MedDRA version: 14.1 Level: LLT Classification code 10041058 Term: Small cell carcinoma of the lung System Organ Class: 100000004864
EUCTR2010-022950-17-GBImmunoGen, Inc181