Locally Applied Pressure-induced Vasodilatation
- Conditions
- Vascular Diseases
- Interventions
- Other: microcirculatory responses
- Registration Number
- NCT02861924
- Lead Sponsor
- University Hospital, Angers
- Brief Summary
Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle).
- Detailed Description
Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle). The purpose of this study is to perform measurements of the methodological points made.
The study will investigate :
* The effect of the duration and intensity of the pressure
* The reproducibility of measurements
* The correlation with ischemic hyperemia post
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
- subjects without vascular pathology
- pregnancy
- allergy tape
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description microcirculatory responses microcirculatory responses Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle). A pressure is applied to the subject's arm. this causes a localized ischemia. the measures responses to this ischemia will be made by the imager speckle (LSCI) give the microvascular perfusion data.
- Primary Outcome Measures
Name Time Method microcirculatory response to local pressure. Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP). 2 hours Measurements are made with the Imager SPECKLE imager (LSCI) give the microvascular perfusion data in arbitrary units called perfusion units (UP).
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU Angers
🇫🇷Angers, France