Effect of Low Level Laser Therapy on Hyper Coagulability in Patients With Covid-19
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Circulatory group laboratory investigation.
研究概览
简要总结
COVID-19 clotting Safety
详细描述
Covid-19 patients have liability for hyper coagulability, low level laser Therapy improve circulation and decrease liability for hyper coagulability accompanied with circulatory exercises .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Care Provider)
盲法说明
circulatory exercise only, circulatory exercises and LLLT.
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI from 18.5 to 29.9 kg/m2
- •Moderate elevated percentage of coagulative factors for COVID-19 Diagnosis:
- •Nasopharyngeal swab
- •Sepsis induced coagulopathy score>4
- •D_dimer≥0,5mg/L
- •Fibrinogen>2,5gm/L
- •C_reactive protein≥10mg/L
- •Lymphocyte count<1,500mm3
- •Platelet count<150,000mm3
- •Prothrombin time increase>3sec
- •Activated partial thromboplastin time increase>5sec
- •Same level of physical activity
- •Patients can swallow tablets
- •CT scan screening method for COVID-19 Diagnosis
- •Physical examination
排除标准
- •hyper tension
- •Cognitive impairment e.g (delirium)
- •Diabetes mellitus both types dependant or non
- •Disabled musculoskeletal Disorders e.g hemi paresis
- •Coronary artery diseases and heart failure
- •Stroke, bone disease, renal failure, pulmonary embolism
- •Vitamins deficiency
- •6 months post large surgeries
- •Alcohol intake and smokers
- •Thyroid diseases
结局指标
主要结局
Circulatory group laboratory investigation.
时间窗: Monthly (an average of two months)
D-dimer≥.5mg/dL, fibrinogen\>2.5mg/dL To examine COVID-19 recovery.
Circulatory group physical examination.
时间窗: Every two days (an average of two months)
by visual analog scale is horizontal line 100mm length the ends defined as extreme limit of the parameter measured (symptom, pain, health) orientated from the left (the worst) the right (the best) 3 times per week to detect DVT.
Circulatory group: CBC analysis.
时间窗: Daily (an average of two months)
Lymphocyte count\<1.500mm3, Platelet count\<150.000mm3, to examine COVID-19 recovery.
Circulatory group (PT, PTT).
时间窗: Bi weekly (an average of two months)
Prothrombin time\>3 sec, activated partial thromboplastin time\>5 sec to examine COVID-19 recovery.
Circulatory group. BMI.
时间窗: Day one
weight kg on height m2 to detect liability for DVT.
Especially Lab investigation.
时间窗: Baseline
C-reactive protein ≥10mg/l for diagnosis of the recovery.
次要结局
- LLLT group CBC analysis.(Daily (an average of two months))
- LLLT group physical examination.(Every two days (an average of two months))
- Specifically Lab investigation.(Baseline)
- LLLT group laboratory investigation.(Monthly (an average of two months))
- LLLT group. {PTT, PT}.(Bi weekly (an average of two months))
- LLLT group. BMI.(Day one)
研究者
Enas Wagdy Elsaid Ahmed
Principal investigator
Cairo University