Comparing the effectiveness, safety, cost and acceptability of salbutamol aerosol inhaler and salbutamol tablet in the treatment of asthma in childre
- Conditions
- Asthma
- Registration Number
- SLCTR/2014/012
- Lead Sponsor
- Base Hospital Embilipitiya
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
1. Clinical diagnosis of acute exacerbation of asthma (see below for case definition)
2. Ages between 6-12 years
3. Receiving in-ward treatment
4. Children who require regular salbutamol in the treatment of acute exacerbation of asthma. This includes
a. Children with severe / moderate acute asthma exacerbation who would be put on regular salbutamol after initial treatment with nebulized salbutamol and other medications
b. Children with mild/moderate asthma who would be straightaway put on regular salbutamol
5.Not used any form of inhaled medications previously
6.Not on nebulized salbutamol at the time of enrollment
7.Not on any other bronchodilators at the time of enrollment
Case definition of Clinically diagnosed to have Bronchial asthma acute exacerbation
1.Previously diagnosed with bronchial asthma (at least one episode with written evidence)
2.Presenting with progressively increasing episodes of shortness of breath, cough, wheeze or chest tightness or combination of these symptoms
3.Presence of bilateral rhonchi on auscultation of lungs
1.Children having long term co-morbidities
2.Children on long term co-medications
3.Children/ parents who cannot be trained to use inhalers for one reason or other
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of children successfully treated children within 3 days. Successful treatment: will be objectively determined using Pulmonary Score” (a validated score) [The blinded outcome assessor (BOA) will be assessing each participant: <br>twice a day when the child is on the intervention and whenever required (maximum duration 3 days)<br>]<br>
- Secondary Outcome Measures
Name Time Method