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Clinical Trials/NCT04759157
NCT04759157
Completed
N/A

A Novel Couples- Based Sleep Health Intervention For Older Adults With Obstructive Sleep Apnea: Implications for Alzheimer's Disease Risk And Healthy Aging

University of Utah1 site in 1 country84 target enrollmentJune 16, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Obstructive Sleep Apnea
Sponsor
University of Utah
Enrollment
84
Locations
1
Primary Endpoint
Recruitment Feasibility
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to develop, refine and evaluate the feasibility of a novel couples-based intervention to improve adherence for patients with obstructive sleep apnea (OSA).

Detailed Description

This study will develop and test a novel couples-based intervention for the treatment of OSA and sleep health among older couples. The focus of this study is patient who are starting CPAP treatment and their partners. Couples will be randomized to a 3-session sleep health intervention delivered via telehealth or to standard educational support for CPAP. The intervention is based on a transdiagnostic model of sleep and circadian disorders (TransS-C) and rooted in the idea that older adults with OSA are often also having other sleep problems, and that OSA is best treated in the couples context.

Registry
clinicaltrials.gov
Start Date
June 16, 2021
End Date
January 31, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kelly Glazer Baron

Associate Professor

University of Utah

Eligibility Criteria

Inclusion Criteria

  • Patient and partner inclusion criteria:
  • Access to cellular (active data plan) or Wi-Fi, in order to complete the telehealth intervention.
  • Patients inclusion criteria:
  • Diagnosed with OSA (AHI\>10 or AHI\>5 with impairment) and intend to start PAP treatment
  • PAP naïve or non-use of PAP for at least 3 years
  • Married or cohabiting with a romantic partner for \>1 year
  • Able to read/write English.
  • Partner inclusion criteria:
  • Able to read/write English
  • PROMIS sleep disturbance score \>55 in either patient or partner, or desire to improve sleep.

Exclusion Criteria

  • Patient only exclusion criteria:
  • Concomitant OSA treatments (bariatric surgery planned in the next 3 months or bariatric surgery in the past year, ear nose and throat surgery for sleep apnea occurring in the 3 months before or planning for within the study period).
  • Exclusion criteria for both patient and partner include the following:
  • High risk or presence of moderate to severe comorbid sleep disorders (i.e., restless legs syndrome)
  • History of cognitive or neurological disorders (e.g., dementia, Parkinson's, Multiple Sclerosis)
  • Presence of major psychiatric disorders (e.g., schizophrenia, bipolar disorder), alcohol abuse reported on the Audit-C (score \>4 for men, \>3 for women), drug use (NIDA-Modified ASSIST score \>3)
  • Unstable or serious medical illness that would interfere with participation (cancer, renal disease on dialysis, moderate to severe COPD)
  • Use of ASV, VPAP or supplemental oxygen
  • Overnight work \> 1x per month
  • Pregnancy/ desire to become pregnant in the study period

Outcomes

Primary Outcomes

Recruitment Feasibility

Time Frame: study duration

Defined as the ability to achieve the recruitment goals of the study, to recruit approximately 3-4 couples per month over the study period (12 months)

Secondary Outcomes

  • Percentage of Days With PAP Use of 4 Hours or More(3 months)
  • Self-reported Sleep Disturbance(3 months)

Study Sites (1)

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