Nitrate for High Intensity Intermittent Exercise

Phase 4

Completed

• Conditions: High Intensity Intermittent Sports Performance
• Interventions: Dietary Supplement: Nitrate-rich concentrated beetroot juice; Dietary Supplement: Nitrate-depleted concentrated red beetroot juice

• Registration Number: NCT02436629
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The objective of the current study is to assess the effect of 6-day dietary nitrate ingestion on high intensity intermittent sports performance in recreational soccer players.

Detailed Description

Oral ingestion of nitrate (NO3-) in the form of both nitrate salts and concentrated red beetroot juice has been shown to significantly lower blood pressure at rest and to improve exercise performance during cycle time trials. Furthermore, a positive exercise performance effect of nitrate ingestion has been observed in recreational athletes during intermittent exercise. However, this was achieved after acute supplementation with a substantial dose of dietary nitrate. Whether similar ergogenic effects of nitrate supplementation can be achieved with a more conventional 6-day nitrate supplementation protocol with a lower daily dose remains to be established. Based on the gaps in current literature, our main goal will be to gain further insight into the effects of a 6-day nitrate supplementation protocol on high intensity intermittent exercise performance in recreational athletes.

Study Timeline

• Study Start: 2015-05
• Study First Submitted: 2015-05-04
• Study First Submitted QC: 2015-05-04
• Study First Posted: 2015-05-07
• Status Verified: 2016-03
• Primary Completion: 2016-04
• Study Completion: 2016-07
• Last Update Submitted: 2016-07-05
• Last Update Posted: 2016-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• Healthy P
• Players of the first two senior selection teams of a regional soccer club competing at the 3rd KNVB level or higher
• Training ≥2 days a week
• 18-40 years
• Male

Exclusion Criteria

• Use of medication
• Injury prohibiting them from performing the exercise protocol effectively
• Smoking
• Currently supplementing diet with nitrate
• Lactose intolerance

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Nitrate-rich concentrated beetroot juice	Nitrate-rich concentrated beetroot juice	Dietary supplement: 800 mg of nitrate in 140 mL of concentrated beetroot juice (Beet-IT)
Nitrate-depleted conc. beetroot juice	Nitrate-depleted concentrated red beetroot juice	Placebo: 140 mL of nitrate-depleted concentrated red beetroot juice

Primary Outcome Measures

Name	Time	Method
Total distance covered during the Yo-Yo Intermittent Recovery 1 test (Yo-Yo IR1 test)	Performance 3 hours post red beetroot juice ingestion

Secondary Outcome Measures

Name	Time	Method
Plasma concentration of nitrite and nitrate	Concetrations 3 hours post red beetroot juice ingestion
Salivary concentration of nitrite and nitrate	Concetrations 3 hours post red beetroot juice ingestion

Trial Locations

Locations (1)

Maastricht University Medical Centre+; 🇳🇱 Maastricht, Limburg, Netherlands