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Economic incentives for improving cure and treatment completion rates in patients with tuberculosis (TB) in South Africa: a study of feasibility and effectiveness

Completed
Conditions
Drug sensitive tuberculosis
Infections and Infestations
Respiratory tuberculosis, not confirmed bacteriologically or histologically
Registration Number
ISRCTN50689131
Lead Sponsor
Medical Research Council of South Africa (South Africa)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
1000
Inclusion Criteria

Current inclusion criteria as of 05/01/2010:
1. With tuberculosis (TB), including re-treatment cases
2. Both men and women, all ages

Initial inclusion criteria at time of registration:
1. Aged 18 years and older
2. With tuberculosis (TB), including re-treatment cases
3. Both men and women

Exclusion Criteria

Current exclusion criteria as of 05/01/2010:
Patients with multi-drug resistant (MDR) or extremely drug-resistent (XDR) TB will be excluded from the analysis. However, they will receive the vouchers for a maximum of 8 months of the study.

Initial exclusion criteria at time of registration:
1. Children less than 18 years
2. Patients with multi-drug resistant (MDR) or extremely drug-resistent (XDR) TB will be excluded from the analysis. However, they will receive the vouchers for a maximum of 8 months of the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Cure: patient who is sputum smear-negative in the last month of treatment and on at least one previous occasion<br>2. Treatment completion: patient who has completed treatment but who does not meet the criteria to be classified as a cure or a failure. (World Health Organization. Global Tuberculosis Control: Surveillance, Planning, Financing. WHO Report 2004).<br><br>These measures will be obtained from the clinic-maintained TB register, in which all patient outcomes are recorded. Outcomes are recorded at the end of patient treatment (6 months for drug sensitive cases, and 8 months for re-treatment).
Secondary Outcome Measures
NameTimeMethod
1. Treatment failure: patient who is sputum smear-positive at 5 months or later during treatment<br>2. Default: patient whose treatment was interrupted for two consecutive months or more. (World Health Organization. Global Tuberculosis Control: Surveillance, Planning, Financing. WHO Report 2004). <br><br>These measures will be obtained from the clinic-maintained TB register, in which all patient outcomes are recorded. Outcomes are recorded at the end of patient treatment (6 months for drug sensitive cases, and 8 months for re-treatment).
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