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Clinical Trials/NCT01394523
NCT01394523
Terminated
Phase 2

A Prospective, Double-blinded, Randomized Comparison of Caudal Analgesia Versus Ultrasound Guided Rectus Sheath Blocks for Umbilical Herniorrhaphy in the Pediatric Population

Nationwide Children's Hospital1 site in 1 country39 target enrollmentAugust 2011
InterventionsBupivacaine

Overview

Phase
Phase 2
Intervention
Bupivacaine
Conditions
Umbilical Hernia
Sponsor
Nationwide Children's Hospital
Enrollment
39
Locations
1
Primary Endpoint
Post-operative Pain Score
Status
Terminated
Last Updated
8 years ago

Overview

Brief Summary

The literature has clearly demonstrated that the effective treatment of postoperative pain in infants and children is challenging. In an effort to improve postoperative analgesia while limiting opioid-related adverse effects, there continues to be an increased use of regional anesthetic techniques in infants and children. Although the pediatric caudal remains the most commonly used pediatric regional anesthetic technique, it has been demonstrated that effective analgesia can be provided with the use of peripheral nerve blockade even in the pediatric-aged patient. The purpose of this study is to prospectively compare post-operative pain relief in pediatric patients undergoing umbilical hernia repair who have received either a caudal block or bilateral rectus sheath blocks for analgesia

Registry
clinicaltrials.gov
Start Date
August 2011
End Date
September 2016
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tarun Bhalla, MD

Attending Anesthesiologist

Nationwide Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • ASA physical status I or II
  • Weight less than or equal to 20 kg
  • Presenting for repair of umbilical hernia

Exclusion Criteria

  • ASA physical status \> II
  • Weight greater than 20 kg
  • Co-morbid diseases (cardiac, pulmonary, neurological disease)
  • Patients having concomitant procedures (circumcision, orchiopexy, etc.)

Arms & Interventions

Caudal epidural

The caudal epidural block will be delivered with 1.5ml/kg of 0.25% Bupivacaine up to a maximum of 30 mL.

Intervention: Bupivacaine

Rectus sheath

The rectus sheath block will be performed with 0.1ml/kg of 0.25% Bupivacaine on each side at the T9-T10 distribution under ultrasound guidance.

Intervention: Bupivacaine

Local

The surgeon will inject either 0.5% Bupivicaine 0.5ml/kg or 0.25% Bupivicaine 1ml/kg at the surgeon's discretion.

Intervention: Bupivacaine

Outcomes

Primary Outcomes

Post-operative Pain Score

Time Frame: 30 minutes

Hannallah et al developed the Objective Pain Scale (OPS) to monitor pain in children after surgery. Parameters: (1) systolic blood pressure, (2) crying, (3) movement, (4) agitation (confused, excited), (5) complains of pain (may not be possible in younger children). Interpretation: minimum score: 0; maximum score: 10; maximum score if too young to complain of pain: 8; the higher the score, the greater the degree of pain.

Study Sites (1)

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