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A Cohort of antithrombotic use and Optimal INR Level in patients with non-valvular atrial fibrillation in Thailand.

Phase 4
Recruiting
Conditions
Patients with non&#45
valvular atrial fibrillation
atrial fibrillation&#44
anticoagulant&#44
warfarin&#44
time in therapeutic range
Registration Number
TCTR20160113002
Lead Sponsor
Health systems research institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
4000
Inclusion Criteria

Patient age > 18 years
Atrial fibrillation recorded from 12-lead ECG, ambulatory monitoring, intracardiac recordings

Exclusion Criteria

Ischemic stroke within 3 months before enrolment
Bleeding disorders
Prosthetic heart valve or valve repair
significant valvular disease
Participating in other blinded clinical trials
Severe comorbidities
Pregnancy
Unable to follow up
Not willing to sign informed consent
Hospitalisation within 1 month
Initiation of warfarin within 1 month

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Optimal INR level 3 years Incidence density
Secondary Outcome Measures
NameTimeMethod
Prevalence and pattern of antithrombotic therapy in patients with atrial fibrillation Cross-sectional Descriptive,Risk of stroke and systemic embolism according to CHADS2 and CHA2DS2VASc score 3 year Descriptive,Risk of bleeding with OAC treatment according to HASBLED and other bleeding risk scores 3 years Descriptive,Time-in-therapeutic range of atrial fibrillation patients who are taking warfarin in Thailand 3 years Rosendaal method,Prevalence of dementia in patients with atrial fibrillation 3 years Screening questionnaire,Prevalence of obstructive sleep apnea in patients with atrial fibrillation 3 years Screening questionnaire
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