Effect of an Anterior Chamber Infusion System on Trabeculectomy Outcomes
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Glaucoma
- Sponsor
- Queen's University
- Locations
- 2
- Primary Endpoint
- surgical success: intraocular pressure lowered by 30% and functional filtering bleb
- Status
- Withdrawn
- Last Updated
- 10 years ago
Overview
Brief Summary
In the treatment of glaucoma, trabeculectomy surgery provides a drainage system for the eye and allows for the lowering of the pressure inside the eye. The flow through the surgically created fistula determines the intraocular pressure. Titrating suture tightness is important to achieving the desired post-operative intraocular pressure. This process is not straightforward and intraocular pressures are often too high or too low post-operatively.
Detailed Description
The use of an anterior chamber infusion system to deliver fluid into the eye during trabeculectomy surgery may be of benefit in this process and may have other benefits as well which may result in better outcomes. Thus, the hypothesis of this study is that the use of an anterior chamber infusion system improves success of trabeculectomy surgery.
Investigators
Dr. Robert Campbell
Principal Investigator
Queen's University
Eligibility Criteria
Inclusion Criteria
- •18 years of age
- •One of the following diagnoses:
- •primary open angle glaucoma
- •chronic angle closure glaucoma
- •pseudo exfoliation glaucoma
- •pigment dispersion glaucoma
Exclusion Criteria
- •unable to provide consent or return for follow up
Outcomes
Primary Outcomes
surgical success: intraocular pressure lowered by 30% and functional filtering bleb
Time Frame: 2 weeks, 1 month, 3 months, 6 months and 1 year post surgery
Secondary Outcomes
- Need for laser suture lysis(any point post operatively)
- complications: aqueous misdirection, suprachoroidal hemorrhage, anterior chamber shallowing(any time post operatively)