Project of Health Promotion and Management for Hepatitis B Carriers in NTU Campus
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Reduction of relative serum HBV DNA levels
Study Overview
Brief Summary
The investigators propose a project of preventive medicine with concern of local context in Taiwan. The target population includes all staff and faculty members, students, and alumni of a university in Northern Taiwan, with chronic hepatitis B infection. The intervention of this project includes standardized lectures, sports courses, nutrition courses, and an information platform. The investigators will evaluate the efficacy after the intervention, like the reduction of hepatitis B viral load and the associated anthropometric parameters. The results of this project will be initially served as a pilot study for this cohort, and applicated as a promising basis for health promotion.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Participants were recruited from students, alumni, faculty and staff members with chronic HBV infection (positive HBsAg serostatus ≥6 months) in a university of northern Taiwan from August 1, 2009 to July 01,
- •Only participants aged 18 and older were included.
Exclusion Criteria
- •Excluded were:
- •(a) those who had been diagnosed as chronic liver diseases like chronic hepatitis C infection (Anti-HCV (+)), autoimmune hepatitis, Wilson disease, alcoholic liver diseases, drug-related hepatitis, decompensated liver diseases, cirrhosis, or malignant hepatic tumors;
- •(b) those who had undergone liver transplantation or major operations for liver except cholecystectomy;
- •(c) men who consumed more than 30 gram of alcohol per week or women who consumed more than 20 gram of alcohol per week;
- •(d) women who were pregnant;
- •(e) those who had current medications for any types of chronic diseases except for hyperglycemia, elevated blood pressure, or dyslipidemia within six months.
Arms & Interventions
Lifestyle conseling
Intervention: standardized exercise program and dietary counseling (Behavioral)
Outcomes
Primary Outcomes
Reduction of relative serum HBV DNA levels
Time Frame: three months
Secondary Outcomes
- anthropometric index(three months)