Extracorporal Membrane Oxygenation for Critically Ill Patients With COVID-19: a Single Centre Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 295
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
Retrospective single center analyses of COVID-19 patients admitted to the ICU between 01/02/2020 and 31/07/2021.
详细描述
All adults (>18 years) with acute hypoxaemic respiratory failure due to diagnosed COVID-19 pneumonia and admitted to ICU from 01/02/2020 until 31/07/2021 were included in the study. Following the World Health Organisation (WHO) protocol 19, laboratory confirmation of COVID-19 infection was defined as a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage. Only laboratory-confirmed patients were included in the analysis.
Additional data collection
Additional collected parameters are listed below and are collected as a standard-of-care in our hospital:
- Demographics: i.e age, gender, BMI
- DNR code
- Comorbidities: smoking, obesity, hypertension, diabetes, cardiovascular disease, respiratory disease, malignancies, renal failure (AKI), liver failure, gastrointestinal disease, neurological conditions, mental state, other
- Symptoms at the time of admission to ICU: i.e fever, body temperature, dyspnoea, headache, diarrhea etc...
- Laboratory results of all standard parameters measured
- Treatment: antiviral agents, antibiotics, etc...
- Complications: shock, heart failure, sepsis, stroke, etc...
- Ventilation: method, PEEP, FiO2, P/F ratio ..
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult COVID-19 patients (>18 years) admitted to the ICU between 01/02/2020 and 31/07/2021 with a laboratory confirmation of COVID-19 infection with a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage
排除标准
- •All adult patients admitted for other reasons to the ICU (no COVID-19 pneumonia)
结局指标
主要结局
Mortality
时间窗: through study completion, an average of 1 year
mortality of patients during their stay at the ICU
次要结局
- 3 Months Mortality(3 months after admission to ICU)
- Length of stay in ICU(during ICU stay)
- acute kidney injury(through study completion, an average of 1 year)
- continous renal replacement therapy(through study completion, an average of 1 year)
- Length of stay in hospital(through study completion, an average of 1 year)
研究者
Stessel Björn
Principal Investigator
Jessa Hospital