ACTRN12621000144819
Completed
未知
A randomised controlled study investigating the effects of two different 12-week aerobic exercise training interventions on cardiorespiratory fitness, brain blood flow, brain volume, and cognitive function in middle-aged adults
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Victoria University
- Enrollment
- 70
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Aged 45\-65
- •\- Able to participate in 36 exercise sessions over 12 weeks
- •\- Normal cognition on screening
- •\- BMI of 18 to 40
- •\- Sign off from doctor to participate in the study
Exclusion Criteria
- •\- Involved in regular exercise training in the previous 6 months
- •\- Significant medical co\-morbidities precluding participation in an exercise intervention (e.g., severe cardiac disease)
- •\- Contraindications to have MRI
- •\- Mild cognitive impairment on screening
- •\- Recent diagnosis (14 days), close contact, or symptomatic of COVID\-19
- •\- Underweight or morbidly obese (BMI \< 18 or \> 40\)
- •\- History of any serious traumatic brain injury (e.g., ICU stay, rehab required, and/or a prolonged period of unconsciousness).
- •\- High blood pressure at rest (over 160/100 mmHg)
- •\- Current or ex\-smoker (last 12 months)
- •\- Any blood disorders or brain tumours
Outcomes
Primary Outcomes
Not specified
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