Comparison of three diagnostic methods to assess albendazole efficacy
Completed
- Conditions
- Soil-transmitted helminthiasis (ascariasis, hookworm disease, trichuriasis)Infections and InfestationsAscariasis
- Registration Number
- ISRCTN90088840
- Lead Sponsor
- Ivo de Carneri Foundation (Italy)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
1. Child judged healthy by study physician
2. Written informed consent provided by child's parent or guardian
3. Provision of stool sample
4. No recent history of anthelminthic treatment (drugs administered within the past 2 weeks)
5. School-aged children between 5 and 16 years (although in some cases this can go as high as 20 years), either sex
Exclusion Criteria
1. Too sick to attend school or participate in the study (e.g. severe diarrhoea, severe anaemia, high fever, etc.)
2. No parental/guardian's permission to participate (absence of written informed consent)
3. Do not provide a stool sample
4. Recent history of anthelminthic treatment (drugs administered within the past 2 weeks)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity of diagnost test, measured at three weeks post-treatment follow-up
- Secondary Outcome Measures
Name Time Method Measured at three weeks post-treatment follow-up:<br>1. Agreement between diagnostic tests for prevalence and infection intensity estimates<br>2. Negative predictive value