Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study

Phase 2

Recruiting

• Conditions: Postoperative Sore Throat
• Interventions: Drug: 10% lidocaine was sprayed over the tube for the second group; Drug: Topical dexamethasone

• Registration Number: NCT06266481
• Lead Sponsor: Pharos University in Alexandria

Brief Summary

postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.

Detailed Description

postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.In this study, 100 patients were intubated to undergo general anaesthesia for shoulder arthroscopy and randomised into one of two groups. An endotracheal tube was soaked in 8mg of dexamethasone for the first group intubation, while 10% lidocaine was sprayed over the tube for the second group. Following extubation, the two groups examined the severity of sore throats

Study Timeline

• Study First Submitted: 2024-01-16
• Status Verified: 2024-02
• Study First Submitted QC: 2024-02-15
• Last Update Submitted: 2024-02-15
• Study First Posted: 2024-02-20
• Last Update Posted: 2024-02-20
• Study Start: 2024-03-01
• Primary Completion: 2024-04-30
• Study Completion: 2024-05-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• •Patients belonging to ASA physical status I, II

  • Patients between age18 to 50 years
  • Patients belonging to both genders.
  • patients undergoing shoulder arthroscopic surgeries.
  • Patients with fasting blood glucose <100 mg/dl or random blood sugar <140 mg/dl.

Exclusion Criteria

• Patients who are not willing to give consent for participation in the study

  • Patients with anticipated difficult airway
  • Patients who are allergic to steroids.
  • Patients with ASA physical status III, IV
  • Diabetic patients.
  • Patients on steroids
  • Patients requiring nasogastric tube or throat pack.
  • Patients posted for head and neck surgeries.
  • patient with GERD
  • Pregnant patients
  • preexisting upper respiratory tract infection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
lidocaine group	10% lidocaine was sprayed over the tube for the second group	10% lidocaine was sprayed over the tube
dexamethasone group	Topical dexamethasone	An endotracheal tube was soaked in 8mg of dexamethasone for group I intubation

Primary Outcome Measures

Name	Time	Method
Topical dexamethasone versus topical lidocaine spray to reduce post-intubation sore throat in shoulder arthroscopic surgeries: A comparative study	3MONTH	This study aimed to compare the effectiveness of topical applications of dexamethasone versus lidocaine spray in prevention sore throat.Patients will be assessed at 1 and 6 h after extubation for post-operative sore throat (POST). POST will be assessed by a modified 4-point scale (0= no sore throat, 1= mild sore throat: complains of sore throat only on asking, 2 = moderate sore throat: complains of sore throat spontaneously, and 3 = severe sore throat: change of voice or hoarseness.

Trial Locations

Locations (1)

Pharos University; 🇪🇬 Alexandria, Egypt