Effect of anesthetics on left ventricular diastolic function in patient with diastolic dysfunction undergoing CABG

Not Applicable

Recruiting

• Conditions: Circulatory System; Surgery; coronary artery bypass grafting

• Registration Number: PACTR201511001243895
• Lead Sponsor: Minoufiya University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-18
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

60 ASA class II or III patients scheduled for CABG surgery by using CPB

Exclusion Criteria

age > 75 years,
left ventricular ejection fraction (LVEF) < 55%,
pre-existing severe LV hypertrophy, cardiomyopathies,
pre-existing valvular heart disease,
grade II (pseudo-normal filling) and grade III (restrictive filling) diastolic dysfunction,
preoperative atrial fibrillation , pericardial disease,
emergency CABG,
significant pulmonary disease
and esophageal pathology.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
trans-mitral diastolic doppler flow profile, tissue doppler imaging (TDI) , pulmonary venous flow velocity

Secondary Outcome Measures

Name	Time	Method
hemodynamic data (HR, MAP and CVP)