A clinical trial to investigate the effect of a proprietary mulberry leaf extract (Reducose®) on lowering blood glucose rises after consuming a drink containing sugar (sucrose)
Not Applicable
Completed
- Conditions
- Postprandial glycaemic controlNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN99601810
- Lead Sponsor
- Phynova Group Limited
- Brief Summary
2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33858439/ (added 13/08/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Consent to study protocol
2. Aged 18-60 years
3. BMI 20-29.9 kg/m²
4. Fasting blood glucose <6.1 mmol/l
Exclusion Criteria
1. Pregnant or lactating
2. Any known food allergies or intolerance to mulberry leaf extracts
3. Presence of a medical condition, or taking medication known to affect glucose regulation and/or influence digestion and absorption of nutrients
4. History of diabetes mellitus (type I or type II), or the use of antihyperglycaemic drugs or insulin to treat diabetes or related conditions
5. Use of steroids, protease inhibitors, or antipsychotics which would affect glucose metabolism and body fat distribution
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incremental area under curve for plasma glucose concentration over 120 min, plasma glucose concentration collected by fingerprick blood sample at 0, 15, 30, 45, 60, 90, and 120 min
- Secondary Outcome Measures
Name Time Method Incremental area under curve for plasma insulin concentration over 120 min, plasma insulin concentration collected by fingerprick blood sample at 0, 15, 30, 45, 60, 90, and 120 min