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Clinical Trials/NCT04928196
NCT04928196
Completed
Not Applicable

Evaluation of Retinal Microvasculature Before and After Silicone Oil Removal by Optical Coherence Tomography Angiography

Kasr El Aini Hospital1 site in 1 country30 target enrollmentJuly 12, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Retinal Vascular
Sponsor
Kasr El Aini Hospital
Enrollment
30
Locations
1
Primary Endpoint
Macular and optic nerve head vascular density
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal.

Detailed Description

Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal. The study includes 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Registry
clinicaltrials.gov
Start Date
July 12, 2021
End Date
October 15, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Kasr El Aini Hospital
Responsible Party
Principal Investigator
Principal Investigator

Hebatalla Makled

Ophthalmology lecturer

Kasr El Aini Hospital

Eligibility Criteria

Inclusion Criteria

  • 30 eyes of 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Exclusion Criteria

  • Proliferative diabetic retinopathy, recurrent detachment or macular hole
  • Patients with chorioretinal degenerations involving the macula
  • Secondary complications as cataract, silicone oil emulsification, or secondary glaucoma
  • Media opacity hindering proper imaging

Outcomes

Primary Outcomes

Macular and optic nerve head vascular density

Time Frame: one year

Using OCTA to assess vascular density changes of the macula and optic nerve head before and after silicone oil removal

Retinal sensitivity by microperimetry

Time Frame: one year

Using microperimetry to assess the retinal sensitivity changes before and after silicone oil removal

Secondary Outcomes

  • Retinal vascular density and best corrected visual acuity(one year)
  • Optic nerve head vascular density and best corrected visual acuity(one year)
  • Retinal sensitivity and best corrected visual acuity(one year)

Study Sites (1)

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