Cariprazine as an adjunct therapy for treatment of negative symptoms in patients with Schizophrenia
- Conditions
- Health Condition 1: F20- Schizophrenia
- Registration Number
- CTRI/2024/07/070875
- Lead Sponsor
- Central Institute of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Schizophrenia diagnosed patients according to International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, ICD-10 Diagnostic criteria.
2) 20–55 years of age.
3) Disease course >2years.
4) PANSS negative symptoms score =4 in at least four items or =15 combined.
5) PANSS positive symptoms score =4 in at least three items or =10 combined.
6) CDSS score <6 and SAS score <3
7) Patients receiving treatment for schizophrenia with preferably second generation anti¬-psychotic
8)Those who give informed consent for
participating in the study.
1.Any other major co-morbid psychiatric diagnosis and substance dependence excluding nicotine & caffeine.
2.Significant medical or neurological illness including severe cardiovascular, hepatic, renal, [serum creatinine > 1.5 mg/dl], anaemia [Haemoglobin < 11 mg/dl], or myopathy or untreated thyroid disease.
3.History of substantial brain damage or any neurological disorders.
4.Pregnancy
5.Patients receiving treatment with any first-generation anti-psychotic / depot or long-acting anti-psychotic / anti-depressant.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method