12 Week, Multi-center, Randomized, Double-blind, Double Dummy, Parallel Group Trial Comparing the Efficacy and Safety of 40 & 80 mg Telmisartan and 50 & 100 mg Losartan in the Treatment of 150 Pairs of Primary Hypertension Patients
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 330
- 主要终点
- Changes in mean sitting valley value of DBP
研究概览
简要总结
Using Losartan as a comparator, to evaluate the efficacy and safety of telmisartan in the treatment of the mild to moderate primary hypertension patients in China
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mild to moderate primary hypertension, the mean sitting valley value of diastolic blood pressure (DBP) ≥ 95 and < 110 mmHg, and the mean sitting valley value of systolic blood pressure (SBP) < 180 mmHg
排除标准
- •Not specified
研究组 & 干预措施
Telmisartan
Low dose of telmisartan, uptitrated to high dose in case no sufficient effect is observered
干预措施: Low dose of telmisartan (Drug)
Telmisartan
Low dose of telmisartan, uptitrated to high dose in case no sufficient effect is observered
干预措施: High dose of telmisartan (Drug)
Losartan
Low dose of losartan, uptitrated to high dose in case no sufficient effect is observered
干预措施: Low dose of losartan (Drug)
Losartan
Low dose of losartan, uptitrated to high dose in case no sufficient effect is observered
干预措施: High dose of losartan (Drug)
结局指标
主要结局
Changes in mean sitting valley value of DBP
时间窗: 8 weeks after start of treatment
The valley value of blood pressure refers to the blood pressure measured prior to the next administration of antihypertensives
次要结局
未报告次要终点